Early mechanical stimulation only permits timely bone healing in sheep
نویسندگان
چکیده
منابع مشابه
Stimulation of Bone Healing in Sheep with a Reinforced Bone Substitute and Colloss®E
INTRODUCTION: The demand for bone graft materials has been increasing dramatically during the past years. Synthetic calcium phosphate bone substitutes, such as hydroxyappatite (HA) and β-Tricalciumphosphate (β-TCP), have received increasing attention due to their similarity in chemical composition with bone and their ability to resorb whilst regenerating new bone. Colloss®E is a lyophilized com...
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Appropriate well-characterized bone defect animal models remain essential for preclinical research. This pilot study demonstrates a relevant animal model for cancellous bone defect healing. Three different defect diameters (8, 11, 14 mm) of fixed depth (25 mm) were compared in both skeletally immature (18-month-old) and aged sheep (5-year-old). In each animal, four defects were surgically creat...
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ژورنال
عنوان ژورنال: Journal of Orthopaedic Research®
سال: 2017
ISSN: 0736-0266
DOI: 10.1002/jor.23812